In a misguided effort to encourage unvaccinated citizens to get a shot, the French President just insulted 13 million of his voters. By doing so, he probably further entrenched the recalcitrants.
Perhaps you work for a company where some employees still refuse to get vaccinated. While it is your duty to try to change their mind (you could literally be saving lives), you must do it with compassion, not contempt.
Once contempt infiltrates a relationship, that relationship is doomed.